The state fire marshal is investigating a fire near St. Robert that killed two children and sent another child and a man to the hospital.
The flames broke out just after 6 p.m. Wednesday.
The Waynesville Rural Fire Protection District was called to the mobile home on Host Drive.
Two of the victims were trapped inside the trailer when crews arrived on scene.
One child was flown to a hospital in Springfield.
The man was rushed to a hospital in Rolla.
The Pulaski County coroner is conducting a death investigation.