Two out-of-state residents were killed in a crash on U-S 60 near Cabool.
The Highway Patrol says a vehicle driven by 31-year-old Larae English of Bridgeport, Alabama, skidded off the left side of the road, rolled across the median into the path of a semi-truck.
English was pronounced dead at the scene.
A passenger, 42-year-old Christopher Thomas of Cowan, Tennessee, died on the way to a hospital.