MoDOT says the ramp to go from James River Freeway eastbound onto northbound Highway 65 in Springfield closed just after 10 a.m. Tuesday after a crash involving a semi, which has been seen hanging off the flyover ramp.
The exit ramp is estimated to be closed for at least an hour and a half.
Crews closed the interchange to traffic to work the crash.
The front wheel of the cab of the semi was dangling from the bridge.